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位置: 首页 > 抑制剂 > YL0919

YL0919#S3648

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称YL0919

简述Inhibitors

纯化98.00%

生物活性YL0919, a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor,the IC50 values of YL-0919 inhibiting the uptake of 5-HT into rat cerebral cortical synaptosomes and human recombinant cells were 1.780.34 nM and 1.930.18 nM respectively.

基因/蛋白名称5-HT Receptor agonist

CAS号1339058-04-6

计算分子量334.84

配方C18H23ClN2O2

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Others
SMILES:Cl.O=C3C=CC=CN3CC2(O)CCN(Cc1ccccc1)CC2
Pathways:GPCR/G Protein; Neuroscience
Receptor:5-HT; 5-HT1A
Boling pt:
Melting pt:
Solubility:Soluble in DMSO
Appearance:Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Chen HX, et al. PLoS One. 2013 Dec 18;8(12):e83271.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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