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位置: 首页 > 抑制剂 > SC1

SC1#S6948

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称SC1

简述Inhibitors

纯化99.00%

生物活性Pluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Maintains embryonic stem cell (ESC) self-renewal.

基因/蛋白名称ERK inhibitor; Raf inhibitor

CAS号839707-37-8

计算分子量550.53

配方C27H25F3N8O2

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Others
SMILES:CN1N=C(C)C=C1NC1=NC=C2CN(C(=O)N(C)C2=N1)C1=CC(NC(=O)C2=CC=CC(=C2)C(F)(F)F)=CC=C1C |c:5,20,31,33,39,41,t:2,9,11,23,29|
Pathways:MAPK
Receptor:ERK1; RasGAP
Boling pt:
Melting pt:
Solubility:Ethanol: <1 mg/mLDMSO: 100 mg/mL (181.64 mM) Water: <1 mg/mL
Appearance:
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Chen S, et al. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17266-71.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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