产品描述
Research Area:Others
SMILES:CCOC1=C(C=CC(=C1)C(C)(C)C)C1=N[C@@](C)(C2=CC=C(Cl)C=C2)[C@](C)(N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1)C1=CC=C(Cl)C=C1 |r,c:5,7,23,51,t:3,14,18,20,46,48|
Pathways:Apoptosis
Receptor:Mdm2
Boling pt:
Melting pt:
Solubility:Ethanol: 100 mg/mL (137.68 mM)
DMSO: 100 mg/mL (137.68 mM)
Water: <1 mg/mL
Appearance:
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Veronica Tisato, et al. MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer. Journal of Hematology & Oncology2017