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位置: 首页 > 重组兔单抗 > BMP2 Rabbit mAb

BMP2 Rabbit mAb#52178

评价
Recombinant
BMP2 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称BMP2 Rabbit mAb

克隆性S03-3H9

亚型Rabbit IgG

纯化Affinity Purified

应用WB

种属反应性Human

免疫原描述Recombinant protein of human BMP2

标记Unconjugated

修饰Unmodification

别名BDA2; BMP2A; SSFSC

数据库入口号Swiss-Prot:P12643
GeneID:650

UniprotP12643

Gene ID650

计算分子量Calculated MW: 45 kDa; Observed MW: 30 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情

WB: 1/1000;

Western blot detection of BMP2 in MCF7,Hela cell lysates using BMP2 Rabbit mAb(1:1000 diluted).Predicted band size:45KDa.Observed band size:30KDa.
背景

Swiss-Prot Acc.P12643.Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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