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位置: 首页 > 单克隆抗体 > LRRK2 (Phospho-Ser935) Rabbit mAb

LRRK2 (Phospho-Ser935) Rabbit mAb #14145

LRRK2 (Phospho-Ser935) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称LRRK2 (Phospho-Ser935) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB ICC/IF

种属反应性Human Mouse

特异性Phospho-LRRK2 (S935) Antibody detects endogenous levels of total Phospho-LRRK2 (S935)

免疫原描述A synthesized peptide derived from human Phospho-LRRK2 (S935)

别名AURA17;Dardarin; LRRK2; LRRK 2; PARK8; RIPK7; ROCO2;

数据库入口号Uniprot:Q5S007

UniprotQ5S007

计算分子量286kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:1000
ICC/IF:1:50~1:200
Western blot analysis of Filamin A phosphorylation expression in WT-LRRK2 cell lysate treated LRRK2.
产品描述
The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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