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位置: 首页 > 单克隆抗体 > PKR (Phospho-Thr446) Rabbit mAb

PKR (Phospho-Thr446) Rabbit mAb#14150

PKR (Phospho-Thr446) Rabbit mAb
PKR (Phospho-Thr446) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称PKR (Phospho-Thr446) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC IP ChIP

种属反应性Human

特异性Phospho-PKR (T446) Antibody detects endogenous levels of total Phospho-PKR (T446)

免疫原描述A synthesized peptide derived from human Phospho-PKR (T446)

别名E2AK2;E2AK2; EIF2AK1; EIF2AK2; MGC126524; PKR p68 kinase; PKR; PRKR;

数据库入口号Uniprot:P19525

UniprotP19525

计算分子量68kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IHC:1:50~1:200
IP:1:50
Western blot analysis of PKR phosphorylation expression in HeLa cell lysate treated with Calyculin A and TNF-alpha.
Immunohistochemical analysis of paraffin-embedded human colon, using Phospho-PKR (T446) Antibody.
产品描述
PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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