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位置: 首页 > 单克隆抗体 > ER alpha (Phospho-Ser118) Rabbit mAb

ER alpha (Phospho-Ser118) Rabbit mAb#14181

ER alpha (Phospho-Ser118) Rabbit mAb
ER alpha (Phospho-Ser118) Rabbit mAb
ER alpha (Phospho-Ser118) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称ER alpha (Phospho-Ser118) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC ICC/IF

种属反应性Human

特异性Phospho-ER alpha (S118) Antibody detects endogenous levels of Phospho-ER alpha (S118)

免疫原描述A synthesized peptide derived from human ER alpha

别名ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha;

数据库入口号Uniprot:P03372

UniprotP03372

计算分子量66kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IHC:1:50~1:200

ICC/IF:1:50~1:200
Western blot analysis of Phospho-ER alpha (S118) expression in (1) MCF7 cell lysate; (2) MCF7 cell lysate treated with b-Estradiol and EGF.
Immunohistochemical analysis of paraffin-embedded human kidney, using Phospho-ER alpha (S118) Antibody.
Immunofluorescent analysis of MCF7 cells treated with EGF, using Phospho-ER alpha (S118) Antibody.
产品描述
Estrogen receptor α (ERα), a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ERα regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ERα activity. ERα is phosphorylated on multiple sites.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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