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位置: 首页 > 单克隆抗体 > CXCR4 Rabbit mAb

CXCR4 Rabbit mAb#56063

CXCR4 Rabbit mAb
CXCR4 Rabbit mAb
CXCR4 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称CXCR4 Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC ICC/IF

种属反应性Human Mouse

特异性CXCR4 Antibody detects endogenous levels of total CXCR4

免疫原描述A synthesized peptide derived from human CXCR4

别名CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;

数据库入口号Uniprot:P61073

UniprotP61073

计算分子量43kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情

WB:1:100~1:200
IHC:1:50~1:200
ICC/IF:1:50~1:200

Western blot analysis of CXCR4 expression in Jurkat cell lysate.
Immunohistochemical analysis of paraffin-embedded human cervical carcinoma, using CXCR4 Antibody.
Immunofluorescent analysis of Jurkat cells, using CXCR4 Antibody .
产品描述

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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