产品名称Recombinant Human Interleukin-1 Receptor Antagonist Protein

来源种属Escherichia coli

纯化> 96 % by SDS-PAGE and HPLC analyses.

生物活性Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α-dependent proliferation of murine D10S cells is less than 40 ng/ml, corresponding to a specific activity of > 2.5 x10⁴ IU/mg in the presence of 50 pg/ml rHuIL-1α.

内毒素Less than 1 EU/ug of rHuIL-1RA as determined by LAL method.

别名IL-1RN, IRAP

UniprotP18510

Gene ID3557

计算分子量Approximately 17.1 kDa, a single non-glycosylated polypeptide chain containing 152 amino acids.

序列RPSGRKSSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDETRLQL EAVNITDLSE NRKQDKRFAF IRSDSGPTTS FESAACPGWF LCTAMEADQP VSLTNMPDEG VMVTKFYFQE DE

配方Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

保存Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ˚C as supplied.- 1 month, 2 to 8 ˚C under sterile conditions after reconstitution.- 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.