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位置: 首页 > 重组蛋白 > Recombinant Exendin-4

Recombinant Exendin-4#AP60499

Recombinant Exendin-4
是否有货: 3-5days
产品总价:
产品详情

产品名称Recombinant Exendin-4

来源种属Escherichia coli

纯化> 96 % by SDS-PAGE and HPLC analyses.

生物活性1. Regulates Glucose levels rapidly;2. Reduces Insulin resistance;3. Reduces Glucagon;4. Reduces HbA1c;5. Stimulates beta cell growth which stimulates insulin production.

内毒素Less than 10 EU/mg of rExendin-4 as determined by LAL method.

别名Exenatide

UniprotP26349

计算分子量Approximately 4.2 kDa, a single non-glycosylated polypeptide chain containing 39 amino acids.

序列HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS

配方Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.

保存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - A minimum of 12 months from date of receipt, when stored at ≤-20 ˚C as supplied. - 1 month, 2 to 8 ˚C under sterile conditions after reconstitution. - 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.

背景
Exendin-4 is a novel 39-amino acid peptide isolated from the venom of the Gila monster Heloderma suspectum. It shares 53% sequence homology with GLP-17-36amide and interacts with the same membrane receptor. Exendin-4 enhances glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying in vivo. It also promotes 脽-cell proliferation and neogenesis in vitro and in animal models. Recombinant Exendin-4 is E. coli expression of a synthetic DNA squence encoding the 39 amino acid of Exendin-4.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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