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位置: 首页 > 磷酸化抗体 > Tyrosine Hydroxylase(Phospho-Ser19) Antibody

Tyrosine Hydroxylase(Phospho-Ser19) Antibody#11329

Tyrosine Hydroxylase(Phospho-Ser19) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Tyrosine Hydroxylase(Phospho-Ser19) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IF

种属反应性Hu Rt

特异性The antibody detects endogenous level of Tyrosine Hydroxylase only when phosphorylated at serine19.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine19 (A-V-S(p)-E-Q) derived from Rat Tyrosine Hydroxylase (TH).

基因/蛋白名称Tyrosine Hydroxylase

修饰Phospho

别名TY3H; TYH; Tyrosine 3-hydroxylase; tyrosine hydroxylase;

数据库入口号Swiss-Prot: P07101
NCBI Protein: NP_036872.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 55-60 kd
Immunofluorescence: 1:100~1:200
Immunofluorescence staining of methanol-fixed Hela cells using Tyrosine Hydroxylase(Phospho-Ser19) Antibody #11329.
背景
The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Vazin T, et al. Stem Cells. 2008 Jun;26(6):1517-25
Pistocchi A, et al. BMC Dev Biol. 2008 Mar 10;8:27
Fukakusa A, et al. J Pharmacol Sci. 2008 Feb;106(2):321-4.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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