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位置: 首页 > 抗体 > HER2(Ab-877) Antibody

HER2(Ab-877) Antibody#21070

HER2(Ab-877) Antibody
HER2(Ab-877) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称HER2(Ab-877) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total HER2 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.875~879 (T-E-Y-H-A) derived from Human HER2.

基因/蛋白名称HER2

别名C-erbB-2; ErbB2;

数据库入口号Swiss-Prot: P04626
NCBI Protein: NP _001005862.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 185kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Western blot analysis of extracts from SKOV3 cells using HER2(Ab-877) Antibody #21070.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HER2(Ab-877) Antibody #21070(left) or the same antibody preincubated with blocking peptide(right).
背景

Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin.

Dittadi, R. et al. (2000) J. Natl. Cancer Inst. 92, 1443-1444.
Muthuswamy, S. K. et al. (1999) Mol. Cell. Biol. 19, 6845-6857.
Qian, X. et al. (1994) Proc. Natl. Acad. Sci. USA 91, 1500-1504.
Kwon, Y. K. et al. (1997) J. Neurosci. 17, 8293-8299.
Klapper, L. N. et al. (2000) Cancer Res. 60, 3384-3388.

如果您使用该产品21070发表了文章,请通知我们,让我们可以引用您的文献。

et al,Loss of Fatty Acid Synthase Inhibits the "HER2-PI3K/Akt Axis" Activity and Malignant Phenotype of Caco-2 Cells.In Lipids Health Dis on 2013 Jun 1 by Nan Li, Heng Lu,et al..PMID:23725225, , (2013),
PMID: 23725225
et al,Fatty Acid Synthase Regulates Proliferation and Migration of Colorectal Cancer Cells via HER2-PI3K/Akt Signaling Pathway.In Nutr Cancer on 2012 Aug by Nan Li, Xiaodong Bu,et al..PMID:22860766, , (2012),
PMID: 22860766
et al,The 鈥淗ER2鈥揚I3K/Akt鈥揊ASN Axis锟?Regulated Malignant Phenotype of Colorectal Cancer Cells. In Lipids on 2012 Apr by Nan Li, Xiaodong Bu, et al..PMID:22218925, , (2012),
PMID: 22218925
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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