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位置: 首页 > 标记抗体 > Pro-Neuregulin 1 Antibody FITC Conjugated

Pro-Neuregulin 1 Antibody FITC Conjugated#C03720F

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产品总价:
产品详情

产品名称 Pro-Neuregulin 1 Antibody FITC Conjugated

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Purified by Protein A.

应用IF(IHC-P)

种属反应性Hu Ms Rt

免疫原描述KLH conjugated synthetic peptide aa 250-300 640 derived from human Pro-Neuregulin 1

标记FITC

激发/发射波长494nm 518nm

基因/蛋白名称Pro-Neuregulin 1

别名GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; Pro-neuregulin-1, membrane-bound isoform; Pro-NRG1; NRG1

数据库入口号Swiss-Prot#Q02297
NCBI Gene ID3084

细胞定位Cytoplasm

浓度1mg ml

配方10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.

保存 Store at 4C for 12 months.

应用详情

Immunofluorescence: 1:50-200

背景

Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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