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位置: 首页 > 磷酸化抗体 > BAD(Phospho-Ser155) Antibody

BAD(Phospho-Ser155) Antibody#11069

BAD(Phospho-Ser155) Antibody
BAD(Phospho-Ser155) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称BAD(Phospho-Ser155) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of BAD only when phosphorylated at serine 155.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine 155(R-M-S(p)-D-E) derived from Human BAD.

基因/蛋白名称BAD

修饰Phospho

别名Bbc2; AI325008

数据库入口号Swiss-Prot: Q61337
NCBI Gene ID: 12015
NCBI mRNA: NM_007522.2
NCBI Protein: NP_031548.1

UniprotQ61337

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C

应用详情

Predicted MW: 23kd

Western blotting: 1:500

Immunohistochemistry: 1:50~1:100

Western blot analysis of extracts from 293 cells using BAD (phospho-Ser155) antibody (#11069).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BAD (phospho- Ser155) antibody (#11069).
背景

 Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Schurmann A., Mooney A.F., Sanders L.C., Sells M.A., Wang H.G., Reed J.C., Bokoch G.M.Mol. Cell. Biol. 20:453-461(2000)
Jakobi R., Moertl E., Koeppel M.A.J. Biol. Chem. 276:16624-16634(2001)        

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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