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位置: 首页 > 磷酸化抗体 > IRS-1(Phospho-Ser307) Antibody

IRS-1(Phospho-Ser307) Antibody#11235

IRS-1(Phospho-Ser307) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称IRS-1(Phospho-Ser307) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of IRS-1 only when phosphorylated at serine 307.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine 307(T-E-S(p)-I-T) derived from Human IRS-1.

基因/蛋白名称IRS-1

修饰Phospho

别名HIRS-1

数据库入口号Swiss-Prot: P35568 ; NCBI Gene ID: 3667; NCBI mRNA: NM_005544.2 ; NCBI Protein: NP_005535.1

UniprotP35568

实际分子量180KD

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C

应用详情
 Predicted MW: 180kd
 Immunohistochemistry: 1:50~1:100
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using IRS-1 (phospho-Ser307) antibody (#11235).
背景

 May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit 

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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