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位置: 首页 > 标记抗体 > YB1(Phospho-Ser102) Antibody Biotin Conjugated

YB1(Phospho-Ser102) Antibody Biotin Conjugated#C04733B

是否有货: 货期15天
产品总价:
产品详情

产品名称YB1(Phospho-Ser102) Antibody Biotin Conjugated

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Purified by Protein A.

应用WB IHC-P

种属反应性Hu Ms Rt

免疫原描述KLH conjugated synthetic phosphopeptide aa 80-120 324 derived from human YB1 around the phosphorylation site of Ser102

标记Biotin

激发/发射波长N A

基因/蛋白名称YB1 Ser102

别名Nuclease-sensitive element-binding protein 1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YB-1; YBX1; NSEP1; YB1

数据库入口号Swiss-Prot#P67809
NCBI Gene ID4904

细胞定位Cytoplasm, Nucleus

浓度1mg ml

配方10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.

保存 Store at 4C for 12 months.

应用详情
Western blotting: 1:100-1000
Immunohistochemistry1:100-500
背景
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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