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位置: 首页 > 抗体 > HDAC2(Ab-394) Antibody

HDAC2(Ab-394) Antibody#21140

HDAC2(Ab-394) Antibody
HDAC2(Ab-394) Antibody
HDAC2(Ab-394) Antibody
HDAC2(Ab-394) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称HDAC2(Ab-394) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB IHC IF

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total HDAC2 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa. 392~396 (E-D-S-G-D) derived from Human HDAC2.

基因/蛋白名称HDAC2

别名HD2; Histone deacetylase 2;

数据库入口号Swiss-Prot: Q92769
NCBI Protein: NP_001518.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 60kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

Western blot analysis of extracts from 293 and Hela cells using HDAC2(Ab-394) Antibody #21140.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HDAC2(Ab-394) Antibody #21140(left) or the same antibody preincubated with blocking peptide(right).
Immunofluorescence staining of methanol-fixed Hela cells using HDAC2(Ab-394) Antibody #21140.
Western Blot analysis of Hela /293 cells using HDAC2 Polyclonal Antibody
背景

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes

Tsai SC, et al.(2002)J Biol Chem; 277(35): 31826-33

如果您使用该产品21140发表了文章,请通知我们,让我们可以引用您的文献。

et al,Growth Attenuation Is Associated With Histone Deacetylase 10-induced Autophagy in the Liver .In J Nutr Biochem on 2016 Jan by Galit Pinto, Biana Shtaif et al..PMID:26462881 , , (2016),
PMID: 26462881
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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