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H2B Antibody#21417

H2B Antibody
是否有货: 有货
产品总价:
产品详情

产品名称H2B Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total H2B protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B.

基因/蛋白名称H2B

别名H2BQ; GL105; H2B.1; H2BFQ; H2BGL105

数据库入口号Swiss-Prot: P33778
NCBI Protein: NP_003519.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 14kd
Western blotting: 1:500~1:1000

Western blot analysis of extracts from Hela and 293 cells using H2B antibody #21417.
背景

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Borchert GM,et al. (2010) PLoS One.5(7):e11641.
Pennini ME,et al.(2010) PLoS Pathog.6(7):e1000995.
Lu C,et al. (2010) Sci China Life Sci.53(6):663-8.

如果您使用该产品21417发表了文章,请通知我们,让我们可以引用您的文献。

et al,The Eaf3/5/7 subcomplex stimulates NuA4 interaction with methylated histone H3 Lys-36 and RNA polymerase II.In J Biol Chem on 2016 Sep 30 by Jake M Lippi, Leah Cohen,et al..PMID:27535225, , (2016),
PMID: 27535225
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com