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Adiponectin Antibody#21665

Adiponectin Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Adiponectin Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total Adiponectin protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.235~239(T-G-F-L-L) derived from Human Adiponectin.

基因/蛋白名称Adiponectin

别名ACDC; ADPN; APM1

数据库入口号Swiss-Prot: Q15848
NCBI Protein: NP_001171271.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 27kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from Rat and Mouse brain tissue using Adiponectin Antibody #21665.
背景
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-a by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Yamauchi T., Kamon J., Waki H. Kadowaki T.Nat. Med. 7:941-946(2001)
Richards A.A., Stephens T., Charlton H.K. Mol. Endocrinol. 20:1673-1687(2006)

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com