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Beclin-1 Antibody#21582

Beclin-1 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Beclin-1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous level of total Beclin-1 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.69-73( F-I-E-T-P) derived from Human Beclin-1.

基因/蛋白名称Beclin-1

别名ATG6; VPS30;

数据库入口号Swiss-Prot: Q14457
NCBI Protein: NP_003757.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 60kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from Raji and K562 cells using Beclin-1 Antibody #21582.
背景
Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Sagona A.P., Nezis I.P., Pedersen N.M., Liestol K., Poulton J., Rusten T.E., Skotheim R.I., Raiborg C., Stenmark H.Nat. Cell Biol. 12:362-371(2010)
Sun Q., Fan W., Chen K., Ding X., Chen S., Zhong Q.Proc. Natl. Acad. Sci. U.S.A. 105:19211-19216(2008)

如果您使用该产品21582发表了文章,请通知我们,让我们可以引用您的文献。

et al,PIWI-Interacting RNA-004800 Is Regulated by S1P Receptor Signaling Pathway to Keep Myeloma Cell Survival.In Front Oncol on 2020 Apr 15 by Ma H, Wang H, et al..PMID: 32351883, , (2020),
PMID: 32351883
et al,Ulva Pertusa Lectin 1 Delivery Through Adenovirus Vector Affects Multiple Signaling Pathways in Cancer Cells.In Glycoconj J on 2017 Aug by Gongchu Li , Zhenzhen Zhao,et al..PMID: 28349379, , (2017),
PMID: 28349379
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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