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位置: 首页 > 磷酸化抗体 > Niban(Phospho-Ser602) Antibody

Niban(Phospho-Ser602) Antibody#11578

Niban(Phospho-Ser602) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Niban(Phospho-Ser602) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous level of Niban only when phosphorylated at serine 602.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine 602 (R-A-S(p)-A-I) derived from Human Niban.

基因/蛋白名称Niban

修饰Phospho

别名FAM129A

数据库入口号Swiss-Prot: Q9BZQ8
NCBI Protein: NP_443198.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 150kd
Western blotting: 1:500~1:1000

Western blot analysis in vitro kinase assays were performed by mixing purified bacterially expressed WT His–Niban or the His–Niban S602A with or without purified active AKT1 using Niban (Phospho-Ser602) Antibody #11578.
背景

Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response

Vill

如果您使用该产品11578发表了文章,请通知我们,让我们可以引用您的文献。

et al,P2X7R Antagonism After Subfailure Overstretch Injury of Blood Vessels Reverses Vasomotor Dysfunction and Prevents Apoptosis.In Purinergic Signal on 2017 Dec by Weifeng Luo, Daniel Feldman,et al..PMID: 28905300, , (2017),
PMID: 28905300
Haitao Ji, Zhiyong Ding, DavidHawke et al,AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis., EUROPEAN MOLECULAR BIOLOGY ORGANIZATION., 6:554-560 (2012),
PMID: 22510990
et al,AKT鈥恉ependent phosphorylation of Niban regulates nucleophosmin鈥恆nd MDM2鈥恗ediated p53 stability and cell apoptosis. In EMBO Rep on 2012 Jun 1 by Haitao Ji, Zhiyong Ding, et al..PMID: 22510990 , , (2012),
PMID: 22510990
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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