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IFIT5 Antibody #35225

IFIT5 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称IFIT5 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用WB

种属反应性Hu

特异性The antibody detects endogenous levels of total IFIT5 protein.

免疫原类型Peptide

免疫原描述Synthesized peptide derived from internal of human IFIT5.

基因/蛋白名称IFIT5

别名IFIT-5; interferon-induced protein with tetratricopeptide repeats 5; retinoic acid- and interferon-inducible 58 kDa protein; RI58;

数据库入口号Swiss-Prot: Q13325
NCBI Gene ID: 24138

UniprotQ13325

实际分子量50kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000

Western blot analysis of extracts from Jurkat cells, using IFIT5 antibody #35225.
背景
Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.

Rogers J., Nature 429:375-381(2004).
Venter J.C., Submitted (SEP-2005).
Bennett K.L., Submitted (OCT-2008).

如果您使用该产品35225发表了文章,请通知我们,让我们可以引用您的文献。

et al,NF-κB-Dependent IFIT3 Induction by HBx Promotes Hepatitis B Virus Replication. In Front Microbiol on 2019 Oct 11 by Xu F, Song H, et al..PMID:31681236, , (2019),
PMID: 31681236
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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