产品详情
产品名称KRT19 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human,Mouse,Rat
特异性The antibody detects endogenous level of total KRT19 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human Cytokeratin 19 (Cytokeratin 19 (KRT19)) (NP_002267.2).
基因/蛋白名称KRT19
别名CK19;K19;K1CS;KRT19
数据库入口号Uniprot:P08727
GeneID:3880
UniprotP08727
Gene ID3880
实际分子量40KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Cytokeratin 19 (KRT19) antibody.
Immunohistochemistry of paraffin-embedded human colon carcinoma using Cytokeratin 19 (Cytokeratin 19 (KRT19)) Rabbit pAb.
Immunohistochemistry of paraffin-embedded Human lung adenocarcinoma using Cytokeratin 19 (Cytokeratin 19 (KRT19)) Rabbit pAb.
Immunohistochemistry of paraffin-embedded human thyroid cancer using Cytokeratin 19 (Cytokeratin 19 (KRT19)) Rabbit pAb.
Immunohistochemistry of paraffin-embedded human colon using Cytokeratin 19 (KRT19) Rabbit pAb.
Immunohistochemistry of paraffin-embedded Human liver (negative control sample) using Cytokeratin 19 (KRT19) Rabbit pAb.
Immunohistochemistry of paraffin-embedded human placenta using Cytokeratin 19 (KRT19) Rabbit pAb.
Immunohistochemistry of paraffin-embedded human tonsil using Cytokeratin 19 (KRT19) Rabbit pAb.
Immunofluorescence analysis of Rat rectum using Cytokeratin 19 (Cytokeratin 19 (KRT19)) antibody.
Immunofluorescence analysis of Mouse large intestine using Cytokeratin 19 (Cytokeratin 19 (KRT19)) antibody.
背景
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.