产品详情
产品名称LACTB2 Antibody FITC Conjugated
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Purified by Protein A.
应用IF(IHC-P)
种属反应性Hu Ms Rt
免疫原描述KLH conjugated synthetic peptide derived from human LACTB2
标记FITC
激发/发射波长494nm 518nm
基因/蛋白名称LACTB2
别名Beta lactamase like protein 2; Beta-lactamase-like protein 2; CGI 83; LACB2_HUMAN; Lactamase beta 2; LACTB2.
数据库入口号
NCBI Gene ID51110
浓度1mg ml
配方10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
保存 Store at 4C for 12 months.
应用详情
Immunofluorescence: 1:50-200
背景
Penicillin refers to any member of beta-lactam antibiotics group. These agents are identified by a beta-lactam ring within their molecular structure. As the most widely used group of antibiotics available, beta-lactams are used for the treatment of bacterial infections usually caused by gram-positive organisms. Beta-lactam antibiotics are bactericidal, functioning to inhibit the synthesis of the peptidoglycan layer of bacterial cell walls. Bacterial penicillin-binding proteins and beta-lactamases constitute a large family of serine proteases that perform essential functions in the synthesis and maintenance of peptidoglycan cell wall. Notably, beta-lactamases cleave beta-lactams, therefore providing the bacteria with resistance to the antibiotic. Homologues of beta-lactamases occur in many species, including human, rat, cow, rabbit, pig, xenopus, zebrafish, and C. elegans. The human homologues, LACTB and LACTB2, are active-site-serine enzymes thought to be involved in metabolism.