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BMAL1 Antibody#21415

BMAL1 Antibody
BMAL1 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称BMAL1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total BMAL1 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.569~573 (S-S-S-I-L) derived from Human BMAL1.

基因/蛋白名称BMAL1

别名MOP3; BMAL1c; ARNTL; TIC;

数据库入口号Swiss-Prot: O00327
NCBI Protein: NP_001025443.1

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 69kd
Western blotting: 1:500~1:1000

Western blot analysis of extracts from mouse brain tissue using BMAL1 antibody #21415.
Western blot analysis of extracts from HL60、THP-1、3T3、HepG2 and MCF7 cells using BMAL1 antibody #21415.
背景

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins

Lee S,et al. (2010) PLoS One.5(6):e10995.
Wang J,et al. (2010) Biosystems.101(2):136-43.
Jung-Hynes ,et al. (2010) J Pineal Res.49(1):60-8.

如果您使用该产品21415发表了文章,请通知我们,让我们可以引用您的文献。

et al,Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice. In Neurobiol Dis on 2021 Oct by Allison R Fusilier, Jennifer A Davis,et al..PMID:34333153, , (2021),
PMID: 34333153
et al,Diurnal Control of Blood Pressure Is Uncoupled From Sodium Excretion. In Hypertension on 2020 Jun by Jermaine G Johnston, Joshua S Speed, et al..PMID:32306766, , (2020),
PMID: 32306766
et al,Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock. In Proc Natl Acad Sci U S A on 2013 Mar 19 by Guangsen Shi, Lijuan Xing, et al..PMID: 23471982, , (2013),
PMID: 23471982
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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