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DNASE1L3 Antibody#36420

DNASE1L3 Antibody
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产品总价:
产品详情

产品名称DNASE1L3 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification.

应用WB

种属反应性Hu

特异性The antibody detects endogenous levels of total DNASE1L3 protein.

免疫原类型Recombinant Protein

免疫原描述Fusion protein corresponding to a region derived from internal residues of human deoxyribonuclease I-like 3

基因/蛋白名称DNASE1L3

别名LSD; DHP2; SLEB16; DNAS1L3

数据库入口号Swiss-Prot#: Q13609
NCBI Gene ID: 1776
Gene Accssion: BC015831

UniprotQ13609

实际分子量36kd

浓度0.9mg/ml

配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500-1:2000
Gel: 8%SDS-PAGE
Lysates (from left to right): HT-29 cell and human placenta tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/450 dilution
Secondary antibody dilution: 1/8000
Exposure time: 30 seconds
背景
This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.?

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et al,Deficient DNASE1L3 facilitates neutrophil extracellular traps-induced invasion via cyclic GMP-AMP synthase and the non-canonical NF-jB pathway in diabetic hepatocellular carcinoma In Clin Transl Immunology on 2022 Apr 20 by Na Li, Xue Zheng, et al..PMID: 35474906, , (2022),
PMID: 35474906
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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