产品详情
产品名称JunB(Phospho-Ser79) Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
应用IHC IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of JunB only when phosphorylated at serine 79.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around phosphorylation site of serine 79 (G-A-S(p)-L-K) derived from Human JunB.
基因/蛋白名称JunB
标记Unconjugated
别名AP-1
数据库入口号Swiss-Prot: P17275
NCBI Protein: NP_002220.1
Uniprot
P17275
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 43kd
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JunB(Phospho-Ser79) Antibody #11026(left) or the same antibody preincubated with blocking peptide(right).
Immunofluorescence staining of methanol-fixed Hela cells using JunB(Phospho-Ser79) Antibody #11026.
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Narayanan K, et al. (2004) J Biol Chem. 279(43): 44294-442302.
如果您使用该产品11026发表了文章，请通知我们，让我们可以引用您的文献。
et al,AP-1 Regulates Cyclin D1 and c-MYC Transcription in an AKT-Dependent Manner in Response to mTOR Inhibition: Role of AIP4/Itch-Mediated JUNB Degradation.
, (2010),
PMID:
21135252
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