产品详情
产品名称Vav(Phospho-Tyr174) Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
应用WB
种属反应性Human;Rat
特异性The antibody detects endogenous level of Vav only when phosphorylated at tyrosine 174.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around phosphorylation site of tyrosine 174 (E-I-Y(p)-E-D) derived from Human Vav.
基因/蛋白名称Vav
标记Unconjugated
别名VAV
数据库入口号Swiss-Prot: P15498
NCBI Protein: NP_005419.2
Uniprot
P15498
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 95kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from Jurkat cells untreated or treated with H2O2 using Vav(Phospho-Tyr174) Antibody #11142.
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation
Amarasinghe GK, et al.
如果您使用该产品11142发表了文章，请通知我们，让我们可以引用您的文献。
et al,Signal-Transducing Adaptor Protein-2 Regulates Stromal Cell-Derived Factor-1 -Induced Chemotaxis in T Cells.
, (2009),
PMID:
19933863
et al,Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1伪-induced chemotaxis in T cells. In J Immunol on 2009 Dec 15 by Yuichi Sekine, Osamu Ikeda,
et al..PMID: 19933863
, (2009),
PMID:
19933863
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