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位置: 首页 > 磷酸化抗体 > Niban(Phospho-Ser602) Antibody

Niban(Phospho-Ser602) Antibody#11578

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产品详情

产品名称Niban(Phospho-Ser602) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Human

特异性The antibody detects endogenous level of Niban only when phosphorylated at serine 602.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine 602 (R-A-S(p)-A-I) derived from Human Niban.

基因/蛋白名称Niban

标记Unconjugated

别名FAM129A

数据库入口号Swiss-Prot: Q9BZQ8
NCBI Protein: NP_443198.1

Uniprot Q9BZQ8

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 150kd
Western blotting: 1:500~1:1000

Western blot analysis in vitro kinase assays were performed by mixing purified bacterially expressed WT His–Niban or the His–Niban S602A with or without purified active AKT1 using Niban (Phospho-Ser602) Antibody #11578.

Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response

Vill

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et al,AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis. , (2012),
PMID: 22510990
et al,AKT鈥恉ependent phosphorylation of Niban regulates nucleophosmin鈥恆nd MDM2鈥恗ediated p53 stability and cell apoptosis. In EMBO Rep on 2012 Jun 1 by Haitao Ji, Zhiyong Ding, et al..PMID: 22510990 , (2012),
PMID: 22510990
et al,P2X7R Antagonism After Subfailure Overstretch Injury of Blood Vessels Reverses Vasomotor Dysfunction and Prevents Apoptosis.In Purinergic Signal on 2017 Dec by Weifeng Luo, Daniel Feldman,et al..PMID: 28905300 , (2017),
PMID: 28905300

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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