产品详情
产品名称YAP (phospho-Ser397) rabbit pAb
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
应用WB
种属反应性Human;Mouse;Rat
特异性This antibody detects endogenous levels of Human Mouse Rat YAP (phospho-Ser397)
免疫原描述Synthesized phosho peptide around human YAP (Ser397)
标记Unconjugated
别名Yorkie homolog (65 kDa Yes-associated protein) (YAP65)
数据库入口号Swiss Prot:P46937
GeneID:10413
Uniprot
P46937
实际分子量67
浓度1 mg/ml
配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
保存-20˚C/1
应用详情
WB 1:1000-2000
Yes associated protein 1(YAP1) Homo sapiens This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],
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et al,MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progressionInEMBO JOn2023 DecbyYan Sun # 1 2, Xin Jin et al..PMID: 37905571
, (2023),
PMID:
37905571