产品详情
产品名称TBK1/NAK (phospho-Ser172) rabbit pAb
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
应用WB
种属反应性Human;Mouse
特异性This antibody detects endogenous levels of Human Mouse TBK1/NAK (phospho-Ser172)
免疫原描述Synthesized phosho peptide around human TBK1 and NAK (Ser172)
标记Unconjugated
别名Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
数据库入口号Swiss Prot:Q9UHD2
GeneID:29110
Uniprot
Q9UHD2
实际分子量80
浓度1 mg/ml
配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
保存-20˚C/1
应用详情
WB 1:1000-2000
TANK binding kinase 1(TBK1) Homo sapiens The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],
如果您使用该产品13488发表了文章，请通知我们，让我们可以引用您的文献。
et al,Activation of cGAS-STING pathway – A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy. In J Clin Lab Anal on 2022 Oct by Meichen Zhou, Xiaoxiao Cheng, et al..PMID:36030554
, (2022),
PMID:
36030554
Yes
