产品详情
产品名称STAT4 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total STAT4 protein.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around aa.691~695 (K-G-Y-V-P) derived from Human STAT4.
基因/蛋白名称STAT4
标记Unconjugated
别名SLEB11
数据库入口号Swiss-Prot: Q14765
NCBI Protein: NP_003142.1
Uniprot
Q14765
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 85kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from Hela, A431 and JK cells using STAT4(Ab-693) Antibody #21047.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT4(Ab-693) Antibody #21047(left) or the same antibody preincubated with blocking peptide(right).
Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
Strausberg R L, et al. (2002) Proc Natl Acad Sci U S A. 99(26):16899-16903.
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et al,A Guanidine-Rich Regulatory Oligodeoxynucleotide Improves type-2 Diabetes in Obese Mice by Blocking T-cell Differentiation. In EMBO Mol Med on 2012 Oct by Xiang Cheng, Jing Wang, et al..PMID:23027613
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PMID:
23027613