产品详情
产品名称STAT5a Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous level of total STAT5A protein.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around aa. 778~782 (R-L-S-P-P) derived from Human STAT5A.
基因/蛋白名称STAT5a
标记Unconjugated
别名MGF, MPF, Mammary gland factor, STA5A, STAT5
数据库入口号Swiss-Prot: P42229
NCBI Protein: NP_003143.2
Uniprot
P42229
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 90kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from K562 cells using STAT5A(Ab-780) Antibody #21049.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT5A(Ab-780) Antibody #21049(left) or the same antibody preincubated with blocking peptide(right).
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.
Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.
Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
如果您使用该产品21049发表了文章,请通知我们,让我们可以引用您的文献。
et al,A Guanidine-Rich Regulatory Oligodeoxynucleotide Improves type-2 Diabetes in Obese Mice by Blocking T-cell Differentiation. In EMBO Mol Med on 2012 Oct by Xiang Cheng, Jing Wang, et al..PMID:23027613
, (2012),
PMID:
23027613