产品详情
产品名称Niban Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用WB IF
种属反应性Human
特异性The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using
epitope-specific immunogen.
免疫原类型Peptide-KLH
免疫原描述peptide sequence around aa. 912~916 (K-E-G-E-G) derived from Human Niban.
基因/蛋白名称Niban
标记Unconjugated
别名FAM129A
数据库入口号Swiss-Prot: Q9BZQ8
NCBI Protein: NP_443198.1
Uniprot
Q9BZQ8
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 150kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200
Western blot analysis of extracts from A431 and DU145 cells using Niban Antibody #21401.
Immunofluorescence staining of methanol-fixed Hela cells using Niban Antibody #21401.
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response
Vill
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et al,AKT鈥恉ependent phosphorylation of Niban regulates nucleophosmin鈥恆nd MDM2鈥恗ediated p53 stability and cell apoptosis. In EMBO Rep on 2012 Jun 1 by Haitao Ji, Zhiyong Ding, et al..PMID: 22510990
, (2012),
PMID:
22510990
et al,Overexpression of zinc鈥恌inger protein 777 (ZNF777) inhibits proliferation at low cell density through down鈥恟egulation of FAM129A.In J Cell Biochem on 2015 Jun by Ryuzaburo Yuki, Kazumasa Aoyama et al..PMID:25560148
, (2015),
PMID:
25560148
et al,Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming. In Oncotarget on 2016 Oct 11 by Irene Riz, Teresa S Hawley,et al..PMID: 27626179
, (2016),
PMID:
27626179
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