BMAL1 Antibody - SAB | Signalway Antibody

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BMAL1 Antibody#21415

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货号规格价格

21415-1 50ul ￥1350元

21415-2 100ul ￥2200元

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产品详情图片产品描述发表文献(3) 其它

产品详情

产品名称BMAL1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Affinity-chromatography

应用WB

种属反应性Human;Mouse;Rat

特异性The antibody detects endogenous level of total BMAL1 protein.

免疫原类型Peptide-KLH

免疫原描述A synthesized peptide derived from human BMAL1

基因/蛋白名称BMAL1

标记Unconjugated

别名MOP3; BMAL1c; ARNTL; TIC;

数据库入口号Swiss-Prot: O00327
NCBI Protein: NP_001025443.1

Uniprot O00327

配方Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

保存Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

应用详情

WB 1:1000-1:2000

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Western blot analysis of BMAL1 expression in human fetal heart lysate.

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes.

如果您使用该产品21415发表了文章，请通知我们，让我们可以引用您的文献。

et al,Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock. In Proc Natl Acad Sci U S A on 2013 Mar 19 by Guangsen Shi, Lijuan Xing, et al..PMID: 23471982 , (2013),
PMID: 23471982

et al,Diurnal Control of Blood Pressure Is Uncoupled From Sodium Excretion. In Hypertension on 2020 Jun by Jermaine G Johnston, Joshua S Speed, et al..PMID:32306766 , (2020),
PMID: 32306766

et al,Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice. In Neurobiol Dis on 2021 Oct by Allison R Fusilier, Jennifer A Davis,et al..PMID:34333153 , (2021),
PMID: 34333153

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注释

应用

WB免疫印迹
IHC免疫组化
IF免疫荧光
ICC免疫细胞化学
FC流式细胞
IP免疫沉淀
E酶联免疫吸附法
DB免疫斑点法
ChIP染色质免疫沉淀
GICA胶体金免疫层析法
NC阴性对照

种属反应性

Hu人
Ms小鼠
Rt大鼠
Dm果蝇
C线虫
Mk猴
Rb兔
B牛
D狗
P猪
Hm仓鼠
ChHm中国仓鼠
Chk鸡

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BMAL1 Antibody#21415

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BMAL1 Antibody#21415

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