产品详情
产品名称N-Cadherin(CD325) Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total N-Cadherin protein.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around aa.800~804(A-I-K-P-V) derived from Human N-Cadherin.
基因/蛋白名称N-Cadherin(CD325)
标记Unconjugated
别名CDH2; CDCN; NCAD
数据库入口号Swiss-Prot: P19022
NCBI Protein: NP_001783.2
Uniprot
P19022
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 140kd
Western blotting: 1:500
Western blot analysis of extract from HT29 cells using N-Cadherin(CD325) Antibody #21474
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density
Bhatt A.S. et.al(2005)Oncogene 24:5333-5343
Salomon D.et.al(1992)J. Cell Sci. 102:7-17
The MGC Project Team(2004)Genome Res. 14:2121-2127
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