产品详情
产品名称CDCP1(CD318) Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用WB
种属反应性Human
特异性The antibody detects endogenous level of total CDCP1(CD318) protein.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around aa.828~832( T-Q-E-P-M) derived from Human CDCP1(CD318).
基因/蛋白名称CDCP1(CD318)
标记Unconjugated
别名TRASK; SIMA135;
数据库入口号Swiss-Prot: Q9H5V8
NCBI Protein: NP_073753.3
Uniprot
Q9H5V8
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 140kd
Western blotting: 1:500
Western blot analysis of extract from Hela cells using CDCP1(CD318) Antibody #21479
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Scherl-Mostageer M., Sommergruber W., Abseher R., Hauptmann R., Ambros P., Schweifer N.
Oncogene 20:4402-4408(2001)
Bhatt A.S., Erdjument-Bromage H., Tempst P., Craik C.S., Moasser M.M.Oncogene 24:5333-5343(2005)
Xia Y., Gil S.G., Carter W.G.J. Cell Biol. 132:727-740(1996)
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