产品详情
产品名称Her3/ErbB3 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total Her3/ErbB3 protein.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around aa. 1326~1330 (P-D-Y-W-H) derived from Human Her3/ErbB3.
基因/蛋白名称Her3/ErbB3
标记Unconjugated
别名 Tyrosine kinase-type cell surface receptor HER3
数据库入口号Swiss-Prot: P21860
NCBI Protein: NP _001005915.1
Uniprot
P21860
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 185kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from A431 cells using Her3/ErbB3(Ab-1328) Antibody #21510.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Her3/ErbB3(Ab-1328) Antibody #21510(left) or the same antibody preincubated with blocking peptide(right).
Binds and is activated by neuregulins and NTAK.
如果您使用该产品21510发表了文章，请通知我们，让我们可以引用您的文献。
et al,Activated ErbB3 translocates to the nucleus via clathrin-independent endocytosis, which is associated with proliferating cells.
In J Biol Chem on 2016 Feb 19 by Raymond Reif, Alshaimaa Adawy,et al..PMID:26719328
, (2016),
PMID:
26719328
有货
