产品详情
产品名称OTUB1 antibody
来源种属Rabbit
克隆性Polyclonal
纯化Purified by antigen-affinity chromatography.
应用WB IF
种属反应性Human
免疫原类型Recombinant protein
免疫原描述Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 119 of Human OTUB1
基因/蛋白名称OTUB1
标记Unconjugated
数据库入口号NCBI Gene ID: 55611
NCBI mRNA#: NM_017670
NCBI Protein#: NP_060140
浓度0.2mg/ml
配方Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
保存Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
应用详情
Predicted MW: 31kd
Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:200
Sample (30 ug of whole cell lysate)
A: Hela
B: Hep G2
12% SDS PAGE
Primary antibody diluted at 1: 1000
Immunofluorescence analysis of methanol-fixed HeLa, using OTUB1 antibody at 1: 50 dilution.
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
如果您使用该产品22056发表了文章，请通知我们，让我们可以引用您的文献。
有货
