产品详情
产品名称SCNN1A antibody
来源种属Rabbit
克隆性Polyclonal
纯化Purified by antigen-affinity chromatography.
应用WB
种属反应性Human
免疫原类型Recombinant protein
免疫原描述Recombinant protein fragment contain a sequence corresponding to a region within amino acids 182 and 429 of SCNN1A
基因/蛋白名称SCNN1A
标记Unconjugated
数据库入口号NCBI Gene ID: 6337
NCBI mRNA#: NM_001038
NCBI Protein#: NP_001029
浓度1mg/ml
配方Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
保存Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
应用详情
Predicted MW: 76kd
Western blotting: 1:500-1:3000
Sample (30 ug of whole cell lysate)
A: Hela
7.5% SDS PAGE
Primary antibody diluted at 1: 1000
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
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et al,E3 ubiquitin ligase Smurf1 promotes cardiomyocyte pyroptosis by mediating ubiquitin-dependent degradation of TRIB2 in a rat model of heart failure
, (2025),
PMID:
39749701
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