产品详情
产品名称GAPDH Antibody
来源种属Chicken
克隆性Polyclonal
纯化Affinity chromatography purified via peptide column
应用ELISA WB
种属反应性Human;Mouse;Rat
免疫原类型Peptide
免疫原描述Raised against a 16 amino acid peptide from near the carboxy terminus of human GAPDH.
基因/蛋白名称GAPDH
标记Unconjugated
别名Glyceraldehyde-3-phosphate dehydrogenase, G3PDH, GAPD
数据库入口号P04406
Uniprot
P04406
浓度1mg/ml
配方Supplied in PBS containing 0.02% sodium azide.
保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
应用详情
Western blot analysis of GAPDH in HeLa cell lysate with GAPDH antibody at 1 ug/mL.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export. GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease. GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
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