产品详情
产品名称ZBTB3 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Affinity chromatography purified via peptide column
应用ELISA WB IHC
种属反应性Human;Mouse;Rat
特异性At least three isoforms of ZBTB3 are known to exist. This antibody is predicted to not cross-react with other ZBTB protein family members.
免疫原类型Peptide
免疫原描述Raised against a 17 amino acid peptide near the carboxy terminus of human ZBTB3.
基因/蛋白名称ZBTB3
标记Unconjugated
别名Zinc finger and BTB domain-containing protein 3
数据库入口号AAH25249
Uniprot
AAH25249
浓度1mg/ml
配方Supplied in PBS containing 0.02% sodium azide.
保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
应用详情
Western blot analysis of ZBTB3 in rat brain tissue lysate with ZBTB3 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry of ZBTB3 in human brain tissue with ZBTB3 antibody at 2.5 ug/mL.
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB3, the related protein ZBTB2 is thought to be phosphorylated in response to the DNA damage, probably by either ATM or ATR. Other ZBTB proteins, such as ZBTB4 and ZBTB38 bind methylated DNA and repress transcription, suggesting that ZBTB3 may also act as a transcription repressor.
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et al,LncKdm2b controls self-renewal of embryonic stem cells via activating expression of transcription factor Zbtb3. In EMBO J. On 2018 Apr 13 by Ye B, Liu B et al..PMID: 29535137
, (2018),
PMID:
29535137
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