产品详情
产品名称BARK1 Monoclonal Antibody
克隆号3F8-G6-C11
来源种属Mouse
克隆性Monoclonal
亚型IgG1
纯化Affinity purified
应用ELISA WB
种属反应性Hu Rt Ms P D
免疫原类型Recombinant protein
免疫原描述Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.
基因/蛋白名称BARK1
标记Unconjugated
别名GRK2, BARK1, BETA-ARK1
Uniprot
P25098
配方Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
应用详情
Predicted MW: 80kd
Western blotting: 1:1000
Western blot detection of ADRBK1 in U937,Raw264.7&Ramos whole cell lysate(1:1000 diluted)
Predicted band size:80KDa.
Observed band size:80KDa.
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.
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