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位置: 首页 > 鼠单克隆抗体 > CBR1 Monoclonal Antibody

CBR1 Monoclonal Antibody#27187

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产品详情

产品名称CBR1 Monoclonal Antibody

克隆号2C9-B12-C4

来源种属Mouse

克隆性Monoclonal

亚型IgG1

纯化Affinity purified

应用WB ICC

种属反应性Human

特异性This antibody detects endogenous levels of CBR1,and does not cross-react with related proteins.

免疫原类型Recombinant Protein

免疫原描述Purified recombinant human CBR1 protein fragments expressed in E.coli

基因/蛋白名称CBR1

标记Unconjugated

别名15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1;

数据库入口号Uniprot: P16152

Gene ID: 873

Uniprot P16152

实际分子量30kd

配方Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol.

保存store at -20˚C

应用详情

Western blotting: 1:1000

Immunocytochemistry: 1:100
Immunocytochemistry stain of Hela using CBR1 antibody (1:100).
Western blot detection of CBR1 in Hela,A431 & MDA-MB-468 cell lysates using CBR1 antibody(1:1000 diluted).Predicted band size:30KDa,Observed band size:30KDa.

 NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.

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注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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