产品详情
产品名称P4HA1 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human P4HA1 (NP_001017962.1).
标记Unconjugated
别名P4HA1;P4HA
数据库入口号Uniprot:P13674
GeneID:5033
Uniprot
P13674
Gene ID
5033
计算分子量61kDa
实际分子量61KDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:1000 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using P4HA1 antibody.
Western blot analysis of extracts of Rat skeletal muscle, using P4HA1 antibody.
Immunofluorescence analysis of L929 cells using P4HA1 Rabbit pAb.
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
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et al,An algorithm-based meta-analysis of genome- and proteome-wide data identifies a combInation of potential plasma biomarkers for colorectal cancer. In Sci Rep on 2019 Oct 30 by Gawel DR, Lee EJ,et al..PMID:31666584
, (2019),
PMID:
31666584
Yes
