产品详情
产品名称GRP78 / BiP Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB;IHC;IF
种属反应性Human;Mouse;Rat
免疫原描述A synthetic peptide of human BiP/GRP78 (NP_005338.1).
标记Unconjugated
别名HSPA5;BIP;GRP78;HEL-S-89n;MIF2
数据库入口号Uniprot:P11021
GeneID:3309
Uniprot
P11021
Gene ID
3309
计算分子量78kDa
实际分子量72-78kDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts from various cell lines using BiP/GRP78 antibody.
Immunohistochemistry of paraffin-embedded rat brain using GRP78 / BiP Polyclonal Antibody.
Immunohistochemistry of paraffin-embedded human liver cancer using GRP78 / BiP Polyclonal Antibody.
Immunohistochemistry of paraffin-embedded human placenta using GRP78 / BiP Polyclonal Antibody.
Immunohistochemistry of paraffin-embedded mouse brain using GRP78 / BiP Polyclonal Antibody.
Immunofluorescence analysis of NIH/3T3 cells using GRP78 / BiP Polyclonal Antibody.
Immunofluorescence analysis of PC-12 cells using GRP78 / BiP Polyclonal Antibody.
Immunofluorescence analysis of U2OS cells using GRP78 / BiP Polyclonal Antibody.
The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.
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et al,Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway. In Biomed Pharmacother
on 2022 Oct by Changlong Fu, Zhiwei Qiu,et al..PMID:35988424
, (2022),
PMID:
35988424
et al,A programmable protease-based protein secretion platform for therapeutic applicationsInNat Chem BiolOn2023 Oct 23byXinyi Wang?#?1,?Liping Kang et al..PMID:?37872400
, (2023),
PMID:
37872400
Yes
