产品详情
产品名称Cleaved Caspase-3 antibody
来源种属Rabbit
克隆性Polyclonal
纯化Immunogen affinity purified
应用WB;IHC
种属反应性Human;Mouse;Rat
特异性Caspase 3 (p17,Cleaved-Asp175) Antibody detects endogenous levels of fragment of activated Caspase 3 resulting from cleavage adjacent to Asp175.
基因/蛋白名称Cleaved-caspase 3
标记Unconjugated
别名Apopain precursor; CASP-3; CPP-32; CPP32; Caspase-3; Cysteine protease CPP32; ICE3; SCA-1; SREBP cleavage activity 1; Yama protein,p17
数据库入口号Swiss-Prot#: P42574
Uniprot
P42574
计算分子量32 kDa
实际分子量17 kDa
浓度1.0mg/ml
配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C/1 year
应用详情
WB: 1:500-1:2000
IHC: 1:50-1:200
Western blot analysis of extracts from Jurkat and MCF7 cells using Cleaved Caspase-3 antibody.
Immunohistochemical analysis of paraffin-embedded Human colon tissue using Cleaved Caspase-3 antibody.
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissue using Cleaved Caspase-3 antibody.
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using Cleaved Caspase-3 antibody.
Immunohistochemical analysis of paraffin-embedded Rat-heart tissue using Cleaved Caspase-3 antibody.
Immunohistochemical analysis of paraffin-embedded Mouse-colon tissue using Cleaved Caspase-3 antibody.
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
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