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GSK3 alpha/beta Antibody#29039

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产品详情

产品名称GSK3 alpha/beta Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Immunogen affinity purified

应用WB IHC

种属反应性Human;Mouse;Rat

特异性GSK3 alpha/beta Antibody detects endogenous levels of total GSK3 alpha/beta

免疫原类型Peptide

免疫原描述A synthesized peptide derived from human GSK3 alpha/beta

基因/蛋白名称GSK3 alpha/beta

标记Unconjugated

别名DKFZp686D0638; glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A

数据库入口号Swiss-Prot#:P49840

Uniprot P49840

实际分子量51,46KD

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C/1 year

应用详情

WB: 1:500-1:2000 

IHC: 1:50-1:200
Western blot analysis of GSK3 alpha/beta expression in TNF-a treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

 GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

如果您使用该产品29039发表了文章,请通知我们,让我们可以引用您的文献。

et al,Effect of electrical stimulation combIned with diet therapy on InsulIn resistance via mTOR signalIng. In Mol Med Rep on 2019 Dec by Huang S, Tang N, et al..PMID:31702811 , (2019),
PMID: 31702811

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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