产品详情
产品名称IL6 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human IL6 (NP_000591.1).
标记Unconjugated
别名IL6;BSF-2;BSF2;CDF;HGF;HSF;IFN-beta-2;IFNB2;IL-6
数据库入口号Uniprot:P05231
GeneID:3569
Uniprot
P05231
Gene ID
3569
计算分子量23kDa
实际分子量23kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using IL6 antibody.
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
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et al,The role of FTO in m6A RNA methylation and immune regulation in Staphylococcus aureus infection-related osteomyelitis.
, (2025),
PMID:
39980685
Yes
