产品详情
产品名称MFGE8 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human MFGE8 (NP_001108086.1).
标记Unconjugated
别名MFGE8;BA46;EDIL1;HMFG;HsT19888;MFG-E8;MFGM;OAcGD3S;SED1;SPAG10;hP47
数据库入口号GeneID:4240
Swiss Prot:Q08431
Uniprot
Q08431
计算分子量35kDa/37kDa/43kDa
实际分子量54kDa
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 209% glycerol.
保存Store at -20˚C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.162.
应用详情
WB 1:500 - 1:2000
IHC 1:100 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using MFGE8 antibody at 1:3000 dilution.
Immunofluorescence analysis of C6 cells using MFGE8 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of L929 cells using MFGE8 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using MFGE8 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
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et al,Quantitative proteomic analysis of scleras in guinea pig exposed to wavelength defocus. In J Proteomics on 2021 Jul 15 by Yingying Wen, Le Jin, et al..PMID:33964483
, (2021),
PMID:
33964483